nexus_hope-2-cmdb.jpg
Healthcare
Operational Resilience
Cyber Resilience
Vulnerability Management

ASL Roma 1’s HOPE: Innovation and Resilience to Vulnerability Waves

Stefano Scaramuzzino
Fabio Battelli
/
Jul 9, 2025

In today’s cybersecurity landscape, where threats evolve at an unprecedented speed, protecting assets in the healthcare sector has become strategically crucial. ASL Roma 1’s HOPE (Healthcare Operational Protection & Excellence) project stands as a cutting-edge initiative in healthcare cybersecurity, leveraging advanced technologies and innovative methodologies to strengthen organizational resilience.

The Strategic Role of the CMDB in the HOPE Project

At the core of HOPE is an advanced approach to Configuration Management Database (CMDB) management. The CMDB is no longer just a static inventory but a dynamic, continuously updated platform capable of:

  • Real-time mapping of all IT and OT assets;

  • Precise classification of each device using updated taxonomies;

  • Supporting rapid, data-driven decision-making.

Thanks to these capabilities, the CMDB becomes a key tool for proactively managing vulnerabilities, especially during waves of CVEs (Common Vulnerabilities and Exposures) that can quickly disrupt complex environments. 

[We will explain more about the innovative things were doing with the CMDB in future articles.]

Integration between assets and vulnerabilities.

Effective Management of CVE Waves

CVE waves are rapid surges of vulnerabilities that can spread swiftly. HOPE, integrated with visibility and threat detection tools, enables:

  • Immediate identification of assets affected by new CVEs through continuous updates and full visibility;

  • Instant impact assessment via intuitive dashboards and automated risk analysis;

  • Planned and orchestrated remediation actions with clear priorities, minimizing response times and operational efforts.

A view of our vulnerability management efforts.

Optimization of Technical and Human Effort

Accurate taxonomy and automated asset management significantly reduce manual intervention. This allows teams to:

  • Focus on the most critical assets;

  • Avoid wasting time on non-relevant elements;

  • Accelerate the entire identification, assessment, and remediation cycle.

The Future Contribution of GenAI in Healthcare Cybersecurity

Looking ahead, the integration of Generative AI (GenAI) into vulnerability management platforms offers a transformative opportunity. GenAI can:

  • Automatically generate customized remediation playbooks based on asset type and the severity of emerging CVEs;

  • Predict the likelihood of vulnerability exploitation by analyzing historical patterns, global threat intelligence, and organizational context;

  • Optimize communication between technical and managerial teams by translating highly technical information into accessible language in real time to support decision-making;

  • Enable dynamic risk scoring with predictive analytics and contextual recommendations.

The adoption of GenAI promises to further reduce response times, enhance the precision of remediation actions, and significantly strengthen proactive resilience in healthcare organizations.

Conclusion

In a scenario where vulnerabilities emerge with unprecedented frequency and impact, the combination of HOPE and visibility and detection tools offers a concrete solution to strengthen cybersecurity posture. The ability to quickly manage vulnerability waves, with reduced human effort and enhanced governance, now represents a vital competitive advantage for healthcare organizations aiming to be resilient and ready for future challenges.

Healthcare
Operational Resilience
Cyber Resilience
Vulnerability Management
Stefano Scaramuzzino
Technical Manager, Cybersecurity ASL Roma 1

Stefano Scaramuzzino is the cybersecurity team leader and network and information systems manager, for ASL Roma 1, Italy's largest local health authority.

Fabio Battelli
Partner, Cyber Risk Services

A partner at Deloitte Italy Cyber Risk Services, Battelli has 25 years consulting experience with a specific focus on ICT/Cybersecurity where he is well-recognized trusted advisor and subject matter expert in critical infrastructure protection (CIP).

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